A voltage-dependent calcium current in mouse MC3T3-E1 osteogenic cells.
نویسندگان
چکیده
MC3T3-E1 osteogenic cells in a growing state were voltage-clamped by the whole-cell patch-clamp method. The MC3T3-E1 cells exhibited a transient, fast-inactivating Ca inward current upon depolarizing pulses from a holding potential of -80 mV. This current had a threshold of activation of about -50 mV and was insensitive to the dihydropyridine, nifedipine. These results show that MC3T3-E1 cells have a voltage-dependent Ca channel corresponding to the "T-type."
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ورودعنوان ژورنال:
- The Japanese journal of physiology
دوره 39 5 شماره
صفحات -
تاریخ انتشار 1989